Article
PARK2/PACRG polymorphisms and susceptibility to typhoid and paratyphoid fever.
Clinical and experimental immunology - 1 Jun 2006
Ali S, Vollaard A M, Widjaja S, Surjadi C, van de Vosse E, van Dissel J T
Abstract excerpt
Host genetic factors may contribute to susceptibility to and outcome in infectious diseases. Recently polymorphisms in PARK2/PACRG, a gene cluster linked to ubiquitination and proteasome-mediated protein degradation, were found to be associated with manifest infection by M. leprae. Here, we address whether these polymorphisms are associated with susceptibility to infection with Salmonella typhi and S. paratyphi...
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