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Article

Apollo, an Artemis-Related Nuclease, Interacts with TRF2 and Protects Human Telomeres in S Phase

26 May 2006

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Share to Chromosomal and Genetic Variations
Share to DNA Repair Mechanisms
Share to Telomeres, Telomerase, and Senescence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16730176
DOI: 10.1016/j.cub.2006.05.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apollo, an Artemis-Related Nuclease, Interacts with TRF2 and Protects Human Telomeres in S PhasePMID 16730176Read ↗

TRF2 and Apollo Cooperate with Topoisomerase 2α to Protect Human Telomeres from Replicative DamageSemantic proximity Read ↗

Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal–Hreidarsson syndromeSemantic proximity Read ↗

Apollo contributes to G overhang maintenance and protects leading-end telomeres.Semantic proximity Read ↗

TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblastsSemantic proximity Read ↗

Structure-Specific nuclease activities of Artemis and the Artemis: DNA-PKcs complexSemantic proximity Read ↗

Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damageSemantic proximity Read ↗

TERRA RNA Antagonizes ATRX and Protects TelomeresSemantic proximity Read ↗

TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNASemantic proximity Read ↗

The Werner Syndrome Helicase and Exonuclease Cooperate to Resolve Telomeric D Loops in a Manner Regulated by TRF1 and TRF2Semantic proximity Read ↗

Apurinic/apyrimidinic endodeoxyribonuclease 2 ( <i>APEX2</i> /APE2) is required for efficient expression of <i>TERT</i> in human embryonic stem cellsSemantic proximity Read ↗

DCLRE1B/hSNM1B (Apollo) is not acutely required for human pluripotent stem cell survivalSemantic proximity Read ↗

A RAP1/TRF2 Complex Inhibits Nonhomologous End-Joining at Human Telomeric DNA EndsSemantic proximity Read ↗

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