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Article

Loss of parafibromin expression in a subset of parathyroid adenomas.

Endocrine-related cancer - 1 Jun 2006

Juhlin C, Larsson C, Yakoleva T, Leibiger I, Leibiger B, Alimov A, Weber G, Höög A, Villablanca A

Abstract excerpt

Inactivation of the hyperparathyroidism-jaw tumour syndrome (HPT- JT) gene, HRPT2, was recently established as a genetic mechanism in the development of parathyroid tumours. Its encoded protein parafibromin has tumour-suppressor properties that play an important role in tumour development in the parathyroids, jaws and kidneys. Inactivating HRPT2 mutations are common in HPT- JT and parathyroid carcinomas, and have...

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Identifiers

PMID: 16728578
DOI: 10.1677/erc.1.01058

Genes

MEN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of parafibromin expression in a subset of parathyroid adenomas.PMID 16728578Read ↗

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