Article
Polymorphisms in ERCC1 and susceptibility to childhood acute lymphoblastic leukemia in a Chinese population.
Leukemia research - 1 Nov 2006
Wang Si Li, Zhao Hui, Zhou Bin, Chen Yong Li, Zou Yao, Zhu Xiao Fan, Li Qing Shan, Han Ming Zhe, Yang Ren Chi, Han Zhong Chao
Abstract excerpt
Excision repair cross-complementation group 1 (ERCC1) is important in repairing DNA damage and genomic instability, and polymorphisms in ERCC1 may play a role in human tumors. In this study, the relationship of two ERCC1 polymorphisms, 8092C>A and 19007G>A, with susceptibility to acute lymphoblastic leukemia (ALL) was investigated in 183 childhood patients. For the ERCC1 8092C>A polymorphism, individuals carrying...
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