Article
Host Lewis phenotype-dependent Helicobacter pylori Lewis antigen expression in rhesus monkeys.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2006
Wirth Hans-Peter, Yang Manqiao, Sanabria-Valentín Edgardo, Berg Douglas E, Dubois André, Blaser Martin J
Abstract excerpt
Both human and H. pylori populations are polymorphic for the expression of Lewis antigens. Using an experimental H. pylori challenge of rhesus monkeys of differing Lewis phenotypes, we aimed to determine whether H. pylori populations adapt their Lewis phenotypes to those of their hosts. After inoculation of four monkeys with a mixture of seven strains identified by RAPD-polymerase chain reaction, H. pylori Lewis...
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