Article
Attenuation and persistence of and ability to induce protective immunity to a Staphylococcus aureus aroA mutant in mice.
Infection and immunity - 1 Jun 2006
Buzzola Fernanda R, Barbagelata María Sol, Caccuri Roberto L, Sordelli Daniel O
Abstract excerpt
Staphylococcus aureus is the most important etiological agent of bovine mastitis, a disease that causes significant economic losses to the dairy industry. Several vaccines to prevent the disease have been tested, with limited success. The aim of this study was to obtain a suitable attenuated aro mutant of S. aureus by transposon mutagenesis and to demonstrate its efficacy as a live vaccine to induce protective...
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