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Article

Attenuation and vaccine potential of aroQ mutants of Corynebacterium pseudotuberculosis.

Infection and immunity - 1 Aug 1997

Simmons C P, Hodgson A L, Strugnell R A

Abstract excerpt

Corynebacterium pseudotuberculosis, a gram-positive intracellular bacterial pathogen, is the etiological agent of the disease caseous lymphadenitis (CLA) in both sheep and goats. Attenuated mutants of C. pseudotuberculosis have the potential to act as novel live veterinary vaccine vectors. We have cloned and sequenced the aroB and aroQ genes from C. pseudotuberculosis C231. By allelic exchange, aroQ mutants of...

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Identifiers

PMID: 9234753
DOI: 10.1128/iai.65.8.3048-3056.1997
PMCID: PMC175430

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Source receipt: pubmed, retrieved 7 Sept 2026.

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