Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VHL and p53: tumor suppressors team up to prevent cancer.

Molecular cell - 19 May 2006

Semenza Gregg L

Abstract excerpt

In a recent issue of Molecular Cell, Roe et al. (2006) report that the von Hippel-Lindau (VHL) protein is a positive regulator of p53, thus providing insight into the mechanisms by which VHL loss of function leads to cancer.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to Genes, p53
Share to Hypoxia-Inducible Factor 1, alpha Subunit
Share to Models, Biological

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neoplasms

Share to Tumor Suppressor Protein p53

Share to von Hippel-Lindau Disease

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Identifiers

PMID: 16713574
DOI: 10.1016/j.molcel.2006.05.001

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VHL and p53: tumor suppressors team up to prevent cancer.PMID 16713574Read ↗

VHL, the story of a tumour suppressor gene.Semantic proximity Read ↗

The Positive Regulation of p53 by the Tumor Suppressor VHLSemantic proximity Read ↗

Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilitiesSemantic proximity Read ↗

Von Hippel-Lindau (VHL) disease: an update on the clinico-pathologic and genetic aspects.Semantic proximity Read ↗

von Hippel-Lindau Disease: an UpdateSemantic proximity Read ↗

Two sides to every story: the HIF-dependent and HIF-independent functions of pVHLSemantic proximity Read ↗

The von Hippel-Lindau tumor suppressor gene.Semantic proximity Read ↗

The VHL tumor suppressor and HIF: insights from genetic studies in mice.Semantic proximity Read ↗

Systemic <i>VHL</i> gene functions and the VHL diseaseSemantic proximity Read ↗

Role of VHL gene mutation in human cancer.Semantic proximity Read ↗

Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer.Semantic proximity Read ↗

Senescence triggered by the loss of the VHL tumor suppressor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.