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Article

A unique strategy for mRNA cap methylation used by vesicular stomatitis virus.

Proceedings of the National Academy of Sciences of the United States of America - 30 May 2006

Li Jianrong, Wang Jennifer T, Whelan Sean P J

Abstract excerpt

Nonsegmented negative-sense (nsNS) RNA viruses typically replicate within the host cell cytoplasm and do not have access to the host mRNA capping machinery. These viruses have evolved a unique mechanism for mRNA cap formation in that the guanylyltransferase transfers GDP rather than GMP onto the 5' end of the RNA. Working with vesicular stomatitis virus (VSV), a prototype nsNS RNA virus, we now provide genetic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16709677
DOI: 10.1073/pnas.0509821103
PMCID: PMC1482520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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