Article
Asporin repeat polymorphism in rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Jan 2007
Torres B, Orozco G, García-Lozano J R, Oliver J, Fernández O, González-Gay M A, Balsa A, García A, Pascual-Salcedo D, López-Nevot M A, Núñez-Roldán A, Martín J, González-Escribano M F
Abstract excerpt
BACKGROUND: Asporin belongs to a family of proteins associated with the cartilage matrix. OBJECTIVE: To investigate the role of the functional polymorphism consisting of an aspartic acid (D) repeat polymorphism located in the ASPN gene in the susceptibility to and clinical outcome of rheumatoid arthritis. METHODS: A total of 803 Spanish Caucasian patients with rheumatoid arthritis and 904 controls of the same...
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