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Article

Spatial covariation of mutation and nonsynonymous substitution rates in vertebrate mitochondrial genomes.

Molecular biology and evolution - 1 Aug 2006

Broughton Richard E, Reneau Paulette C

Abstract excerpt

Mitochondrial genomes encode fundamental subunits of the basic energy producing machinery of eukaryotic cells that are under strong functional constraint. Paradoxically, these genes evolve rapidly in general, and there is substantial variation in evolutionary rates among genes within genomes. In order to investigate spatial variation in selection intensity, we conducted tests of neutrality using ratios of...

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PMID: 16705079
DOI: 10.1093/molbev/msl013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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