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Article

A polymorphism in the agouti signaling protein gene is associated with human pigmentation.

American journal of human genetics - 1 Mar 2002

Kanetsky Peter A, Swoyer Jennifer, Panossian Saarene, Holmes Robin, Guerry DuPont, Rebbeck Timothy R

Abstract excerpt

In mice and humans, binding of alpha-melanocyte--stimulating hormone to the melanocyte-stimulating--hormone receptor (MSHR), the protein product of melanocortin-1 receptor (MC1R) gene, leads to the synthesis of eumelanin. In the mouse, ligation of MSHR by agouti signaling protein (ASP) results in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11833005
DOI: 10.1086/339076
PMCID: PMC384954

Genes

ASIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11833005-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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