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Mesothelin Variant 1 Is Released from Tumor Cells as a Diagnostic Marker

1 May 2006

Abstract excerpt

The mesothelin family comprises (at least) three variants and includes the precursor for megakaryocyte potentiating factor (MPF). Assaying soluble mesothelin-related protein (SMRP) molecules in serum and other body fluids from patients with certain cancers can provide diagnostically useful information. We have constructed fusion proteins of mesothelin variants 1, 2, and 3, made monoclonal antibodies, and...

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PMID: 16702385
DOI: 10.1158/1055-9965.epi-05-0334

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