Article
MHC class I chain-related gene B promoter polymorphisms and celiac disease.
Human immunology - 1 Mar 2006
Rodriguez-Rodero Sandra, Rodrigo Luis, Fdez-Morera Juan Luis, Martinez-Borra Jesus, Lopez-Vázquez Antonio, Fuentes Dolores, Lopez-Arbesu Ruben, Lopez-Soto Alejandro, Gonzalez Segundo, Lopez-Larrea Carlos
Abstract excerpt
The possibility that susceptibility to celiac disease (CD) might be influenced by the MHC class I chain-related gene family, MICA and MICB, has been previously reported. In this study, we analyzed the MICB promoter and examined the association of the polymorphisms found within such in a group of CD patients. To study the MICB promoter we sequenced the 5' flanking region of MICB gene in DNA from homozygous...
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