Article
MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ.
Human immunology - 1 Jan 2000
Van Autreve Jan E, Koeleman Bobby P C, Quartier Erik, Aminkeng Folefac, Weets Ilse, Gorus Frans K, Van der Auwera Bart J R
Abstract excerpt
To ascertain association of MICA with type 1 diabetes (T1D) in the Belgian population, well-characterized antibody-positive patients were analyzed for MICA transmembrane gene polymorphism in both an association study and a nuclear family study. The frequency of MICA5 was significantly increased in the T1D patient group (18%) compared with the control population (12%, OR=1.6, pc<10(-3)), whereas MICA9 was...
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