Article
First report of knockdown mutations in the malaria vector Anopheles gambiae from Cameroon.
The American journal of tropical medicine and hygiene - 1 May 2006
Etang Josiane, Fondjo Etienne, Chandre Fabrice, Morlais Isabelle, Brengues Cecile, Nwane Philippe, Chouaibou Mouhamadou, Ndjemai Hamadou, Simard Frédéric
Abstract excerpt
We report the first finding of the knockdown Leu-Phe and Leu-Ser mutations associated with resistance to pyrethroids and DDT insecticides in the malaria mosquito Anopheles gambiae from Cameroon. The Leu-Phe mutation was found in both the M and S molecular forms of An. gambiae. Importantly, two specimens of the S molecular form were found to carry both mutations in a heterozygous state.
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