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Article

Relationship Between kdr Mutation and Resistance to Pyrethroid and DDT Insecticides in Natural Populations of Anopheles gambiae

2008-03-01

Abstract excerpt

The spread of insecticide resistance genes in Anopheles gambiae Giles sensu stricto threatens to compromise vector-based malaria control programs. Two mutations at the same locus in the voltage-gated sodium channel gene are known to confer knockdown resistance (kdr) to pyrethroids and DDT. Kdr-e involves a leucine-serine substitution, and it was until recently thought to be restricted to East Africa, whereas kdr-w...

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Literature Corpus work
7b0d115c-2ad8-5031-a354-8c7aeb578bd5
DOI
10.1093/jmedent/45.2.260
Open publication

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Relationship Between kdr Mutation and Resistance to Pyrethroid and DDT Insecticides in Natural Populations of Anopheles gambiaeDOI 10.1093/jmedent/45.2.260
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