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Article

Activating mutations in the luteinizing hormone receptor gene: a human model of non-follicle-stimulating hormone-dependent inhibin production and germ cell maturation.

The Journal of clinical endocrinology and metabolism - 1 Aug 2006

Soriano-Guillen Leandro, Mitchell Valerie, Carel Jean-Claude, Barbet Patrick, Roger Marc, Lahlou Najiba

Abstract excerpt

CONTEXT: Familial male-limited precocious puberty is a dominant autosomal genetic disease caused by activating LH receptor gene mutations, clinically expressed only in males. In preliminary studies, in addition to the expected testosterone increase, we found high inhibin B levels before the age of normal puberty. OBJECTIVES: The objective of the study was to assess the cellular origin of serum inhibin thanks to...

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Identifiers

PMID: 16684832
DOI: 10.1210/jc.2005-2564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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