Article
Mutations along the pituitary-gonadal axis affecting sexual maturation: novel information from transgenic and knockout mice.
Molecular and cellular endocrinology - 25 Jul 2006
Huhtaniemi Ilpo
Abstract excerpt
During the last 10 years, numerous activating and inactivating mutations have been detected in the genes encoding the two gonadotrophins, luteinising hormone (LH) and follicle-stimulating hormone (FSH), as well as their cognate receptors (R), LHR and FSHR. Because activation of the hypothalamic-p...
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