Article
The effect of distinct activating mutations of the luteinizing hormone receptor gene on the pituitary-gonadal axis in both sexes.
Clinical endocrinology - 1 Nov 2000
Latronico A C, Lins T S, Brito V N, Arnhold I J, Mendonca B B
Abstract excerpt
OBJECTIVE: Familial or sporadic male-limited precocious puberty is a distinct and unusual gonadotrophin-independent form of sexual precocity caused by constitutively activating mutations of the luteinizing hormone receptor (LHR). In the present study, we evaluated the effect of known activating m...
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