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Transcriptional regulation of the methuselah gene by dorsal protein in Drosophila melanogaster.

Molecules and cells - 30 Apr 2006

Kim Hyukmin, Kim Jinsu, Lee Yoonsoo, Yang Jaeyeon, Han Kyuhyung

Abstract excerpt

The Drosophila methuselah (mth) mutant has an approximately 35 percent increase in average lifespan, and enhanced resistance to various forms of stress, including starvation, high temperature, and dietary paraquat. To examine the transcriptional regulation of mth, we used luciferase assays employing Drosophila S2 cells. Two positive control elements were found at -542 to -272 (PE1) and +28 to +217 (PE2), where...

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PMID: 16682822

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RHD

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