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Article

Alterations in anti-oxidative defence enzymes in erythrocytes from sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients.

Clinical chemistry and laboratory medicine - 1 Jan 2006

Nikolić-Kokić Aleksandra, Stević Zorica, Blagojević Dusko, Davidović Biljana, Jones David R, Spasić Mihajlo B

Abstract excerpt

BACKGROUND: Overproduction of nitric oxide (NO) and hydrogen peroxide (H(2)O(2)) may be an important factor in the pathogenesis of amyotrophic lateral sclerosis (ALS). Owing to their ability to permeate through biological membranes, excess NO and H(2)O(2) may be present in the media surrounding motor neurones. Anti-oxidative defence enzymes (ADEs) in erythrocytes are capable of detoxifying reactive oxygen species...

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Source

Identifiers

PMID: 16681429
DOI: 10.1515/CCLM.2006.111

Genes

CAT
SOD1
DDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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