Article
Single nucleotide polymorphisms: early diagnosis and risk assessment in genitourinary malignancy.
Urologic oncology - 1 Jan 2000
Kibel Adam S
Abstract excerpt
Genetic screening for malignancy has been limited to high-risk individuals with a strong hereditary predisposition to cancer. With the cloning of the human genome, it has become apparent that genetic anomalies are not limited to high-risk individuals; more than 10 million genetic variants exist. Because the vast majority of these genetic variants have no functional significance, current efforts are focused on...
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