Article
Fluoride down‐regulates the expression of matrix metalloproteinase‐20 in human fetal tooth ameloblast‐lineage cells in vitro
1 May 2006
Abstract excerpt
Fluoride is associated with a decrease in the incidence of dental caries, but excessive fluoride intake during tooth enamel formation can result in enamel fluorosis. Fluorosed enamel has increased porosity, which has been related to a delay in the removal of amelogenin proteins as the enamel matures. This delay in protein removal suggests that fluoride may affect either the amount or the activity of enamel matrix...
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