Article
Enamel proteins and proteases in Mmp20 and Klk4 null and double-null mice.
European journal of oral sciences - 1 Dec 2011
Yamakoshi Yasuo, Richardson Amelia S, Nunez Stephanie M, Yamakoshi Fumiko, Milkovich Rachel N, Hu Jan C-C, Bartlett John D, Simmer James P
Abstract excerpt
Matrix metalloproteinase 20 (MMP20) and kallikrein-related peptidase 4 (KLK4) are thought to be necessary to clear proteins from the enamel matrix of developing teeth. We characterized Mmp20 and Klk4 null mice to better understand their roles in matrix degradation and removal. Histological examination showed retained organic matrix in Mmp20, Klk4, and Mmp20/Klk4 double-null mouse enamel matrix, but not in the...
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