Article
Multiple imputation of missing genotype data for unrelated individuals.
Annals of human genetics - 1 May 2006
Souverein O W, Zwinderman A H, Tanck M W T
Abstract excerpt
The objective of this study was to investigate the performance of multiple imputation of missing genotype data for unrelated individuals using the polytomous logistic regression model, focusing on different missingness mechanisms, percentages of missing data, and imputation models. A complete dataset of 581 individuals, each analysed for eight biallelic polymorphisms and the quantitative phenotype HDL-C, was...
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