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Article

Variable expression patterns of Mycobacterium tuberculosis PE_PGRS genes: evidence that PE_PGRS16 and PE_PGRS26 are inversely regulated in vivo.

Journal of bacteriology - 1 May 2006

Dheenadhayalan Veerabadran, Delogu Giovanni, Sanguinetti Maurizio, Fadda Giovanni, Brennan Michael J

Abstract excerpt

Evaluation of expression of 16 PE_PGRS genes present in Mycobacterium tuberculosis under various growth conditions demonstrated constitutive expression of 7 genes, variable expression of 7 genes, and no expression of 2 genes. An inverse expression profile for genes PE_PGRS16 and PE_PGRS26 was observed to occur in macrophages and in mice infected with M. tuberculosis. Variable expression of PE_PGRS proteins could...

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Identifiers

PMID: 16672626
DOI: 10.1128/JB.188.10.3721-3725.2006
PMCID: PMC1482869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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