Structures of ubiquitin insertion mutants support site-specific reflex response to insertions hypothesis.

Abstract excerpt

We previously concluded that, judging from NMR chemical shifts, the effects of insertions into ubiquitin on its conformation appear to depend primarily on the site of insertion rather than the sequence of the insertion. To obtain a more complete and atomic-resolution understanding of how these insertions modulate the conformation of ubiquitin, we have solved the crystal structures of four insertional mutants of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Crystallography, X-Ray
• Share to Models, Molecular