Article
Structure of a hinge-bending bacteriophage T4 lysozyme mutant, Ile3-->Pro.
Journal of molecular biology - 5 Oct 1992
Dixon M M, Nicholson H, Shewchuk L, Baase W A, Matthews B W
Abstract excerpt
The mutant T4 phage lysozyme in which isoleucine 3 is replaced by proline (I3P) crystallizes in an orthorhombic form with two independent molecules in the asymmetric unit. Relative to wild-type lysozyme, which crystallizes in a trigonal form, the two I3P molecules undergo large hinge-bending disp...
Topics
- Bacteriophage T4
- Crystallization
- Hydrogen Bonding
- Models, Molecular
- Muramidase
- Mutation
- Protein Conformation
- Protein Structure, Secondary
- Protein Structure, Tertiary
- Temperature
- X-Ray Diffraction