Article
Breast cancer proteomics by laser capture microdissection, sample pooling, 54-cm IPG IEF, and differential iodine radioisotope detection.
Electrophoresis - 1 May 2006
Neubauer Hans, Clare Susan E, Kurek Raffael, Fehm Tanja, Wallwiener Diethelm, Sotlar Karl, Nordheim Alfred, Wozny Wojciech, Schwall Gerhard P, Poznanović Slobodan, Sastri Chaturvedula, Hunzinger Christian, Stegmann Werner, Schrattenholz André, Cahill Michael A
Abstract excerpt
The presence of progesterone receptor (PR) in estrogen receptor (ER)-positive breast cancer is associated with a good prognosis, and indicates that tumors are likely to respond to tamoxifen. However, ER+/PR- tumors respond less well. To reveal the potential molecular mechanism of this phenomenon, we sought to identify differential protein abundances between invasive ductal carcinoma cells from cryopreserved...
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