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Article

The major role of Spo0A in genetic competence is to downregulate abrB, an essential competence gene.

Journal of bacteriology - 1 Jun 1995

Hahn J, Roggiani M, Dubnau D

Abstract excerpt

We show that the major role for Spo0A in the development of genetic competence is to downregulate expression of abrB. AbrB is both a negative regulator and a positive regulator of competence. The negative effects are exerted at multiple points in competence regulation. A regulatory mechanism that is independent of mecA and abrB operates on comK expression.

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Identifiers

PMID: 7768874
DOI: 10.1128/jb.177.12.3601-3605.1995
PMCID: PMC177070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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