Article
Suppressors of a spo0A missense mutation and their effects on sporulation in Bacillus subtilis.
Biochimie - 1 Jan 2000
Grossman A D, Lewis T, Levin N, DeVivo R
Abstract excerpt
The spo0A gene product of Bacillus subtilis is a transcriptional regulator that is required for the initiation of sporulation. It has not been possible to isolate mutations that suppress the sporulation defect caused by spo0A null mutations. We describe the isolation and characterization of mutations that suppress the severe sporulation defect caused by a spo0A missense mutation (spo0A9V). Two suppressor...
Topics
- Bacillus subtilis
- Bacterial Proteins
- Cloning, Molecular
- Genes, Bacterial
- Mutagenesis
- Mutation
- Phenotype
- Plasmids
- Spores, Bacterial
- Suppression, Genetic
- Transcription Factors
- Transcription, Genetic