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Article

Are serum leptin and the Gln223Arg polymorphism of the leptin receptor determinants of bone homeostasis in elderly men?

European journal of endocrinology - 1 May 2006

Crabbe Patricia, Goemaere Stefan, Zmierczak Hans, Van Pottelbergh Inge, De Bacquer Dirk, Kaufman Jean-Marc

Abstract excerpt

OBJECTIVE: Across studies it has been suggested that leptin intervenes as a regulator of bone metabolism. This study assesses the contribution in elderly men of leptin and the Gln223Arg leptin receptor gene (LEPR) polymorphism to the variation in bone homeostasis, in relation to body composition and free estradiol as major confounders. DESIGN: We performed cross-sectional (n = 270) and longitudinal (mean...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16645018
DOI: 10.1530/eje.1.02130

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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