Article
A combined effect of the KPNA3 and KPNB3 genes on susceptibility to schizophrenia.
Neuroscience letters - 10 Jul 2006
Zhang Haiying, Ju Guizhi, Wei Jun, Hu Ying, Liu Libo, Xu Qi, Chen Yang, Sun Zhiwei, Liu Shuzheng, Yu Yaqin, Guo Yingjun, Shen Yan
Abstract excerpt
Recent studies suggest that both the KPNB3 gene and the KPNA3 gene in the long arm of chromosome 13 (13q) are associated with schizophrenia. Because these two genes belong to the same family of karyopherins, their combined effect on illness was investigated among 238 Chinese family trios consisting of fathers, mothers and affected offspring with schizophrenia. We detected three single nucleotide polymorphisms...
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