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Is KPNB3 locus associated with schizophrenia?

Biomedical and environmental sciences : BES - 1 Feb 2007

Liu Li-Bo, Hu Ying, Ju Gui-Zhi, Zhang Xuan, Xie Lin, Liu Shu-Zheng, Shi Jie-Ping, Yu Ya-Qin, Xu Qi, Fan Yu, Shen Yan, Wei Jun

Abstract excerpt

OBJECTIVE: To reconfirm the association of KPNB3 with schizophrenia in Chinese population. METHODS: Two single nucleotide polymorphisms (SNPs), rs2588014 and rs626716 at the KPNB3 locus, were genotyped in 304 Chinese Han family trios consisting of fathers, mothers, and affected offsprings with schizophrenia. These 2 SNPs were detected by PCR-based restriction fragment length polymorphism (RFLP) analysis. The...

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PMID: 17458142

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