Article
Knockdown of annexin 2 decreases migration of human glioma cells in vitro
22 Feb 2006
Abstract excerpt
Diffuse invasion of brain tissue is a major reason for the poor prognosis of patients with glioblastoma. Annexin 2, a member of the large annexin family of Ca2+ and membrane-binding proteins, is expressed at high protein levels in human gliomas and has been proposed as a marker of glioma malignancy, while its functional role in these tumours is unknown so far. The ability of annexin 2 to interact with the actin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.