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Article

Downregulation of ABCG2 protein inhibits migration and invasion in U251 glioma stem cells

28 Apr 2014

Abstract excerpt

ABCG2 is a member of the ATP-binding cassette transporter family, which has been detected in a wide variety of human aggressive tumors, including glioma stem cells (GSCs), glioma tissues of higher grades, and implanted glioma xenografts. Previous research has implied that ABCG2 might be associated closely with invasion and spread in tumors. However, the specific roles and mechanisms of ABCG2 in regulating the...

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PMID: 24781949
DOI: 10.1097/wnr.0000000000000161

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