Article
Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis.
Journal of neuro-oncology - 1 Jun 2001
Mariani L, Beaudry C, McDonough W S, Hoelzinger D B, Demuth T, Ross K R, Berens T, Coons S W, Watts G, Trent J M, Wei J S, Giese A, Berens M E
Abstract excerpt
Microarray analysis of complementary DNA (cDNA) allows large-scale, comparative, gene expression profiling of two different cell populations. This approach has the potential for elucidating the primary transcription events and genetic cascades responsible for increased glioma cell motility in vitro and invasion in vivo. These genetic determinants could become therapeutic targets. We compared cDNA populations of a...
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