Article
Overrepresentation of the N363S variant of the glucocorticoid receptor gene in patients with bilateral adrenal incidentalomas.
The Journal of clinical endocrinology and metabolism - 1 Jul 2006
Majnik Judit, Patocs Attila, Balogh Katalin, Toth Miklos, Gergics Peter, Szappanos Agnes, Mondok Agnes, Borgulya Gabor, Panczel Pal, Prohaszka Zoltan, Racz Karoly
Abstract excerpt
CONTEXT: Some variants of the glucocorticoid receptor (GR) gene have been found to alter glucocorticoid sensitivity and have been associated with altered metabolic profiles. OBJECTIVE: The objective of the study was to examine whether N363S and ER22/23K variants of the GR gene may be associated with the development of adrenal incidentalomas and whether these variants may contribute to metabolic abnormalities...
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