Article
[Experiment on induction of fibroblasts on 3-D cell-foam structures to express osteoblastic phenotype and its mechanism].
Zhonghua wai ke za zhi [Chinese journal of surgery] - 15 Feb 2006
He Chuan, Deng Lian-fu, Yang Qing-ming, Shen Wei, Feng Wei, Zhang Yue, Zhu Ya-ping
Abstract excerpt
OBJECTIVE: To study the feasibility of osteogenic phenotype expression by human skin fibroblasts induced in polyglycolic acid (PGA) foams and the effect of tumor necrosis factor-alpha (TNF-alpha) on the expression of bone morphogenetic protein (BMP) receptors. METHODS: The fibroblasts were isolated, purified from human skin. (1) Fibroblasts were seeded onto PGA foams. The cell-PGA complexes were cultured in RCCS...
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