Article
[Cartilage-derived morphogenetic protein 1 initiates chondrogenic differentiation of human dermal fibroblasts in vitro].
Zhonghua yi xue za zhi - 2 Aug 2004
Cui Lei, Yin Shuo, Deng Chen-liang, Yang Guang-hui, Chen Fu-guo, Liu Wei, Liu De-li, Cao Yi-lin
Abstract excerpt
OBJECTIVE: To investigate the feasibility of human dermal fibroblasts in vitro differentiation into chondrogenic phenotype with induction of cartilage-derived morphogenetic protein (CDMP) growth factor. METHODS: Human dermal fibroblasts were isolated from foreskin and cultured in monolayer ex vivo. Dermal fibroblasts of passage2 was plated at density of 1 x 10(4) cells/cm(2) and induced with CDMP1 (100 ng/ml) in...
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