Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Effects of hypoxia on the phenotype transformation of human dermal fibroblasts to myofibroblasts and the mechanism].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns - 20 Jun 2017

Zhao B, Han F, Zhang W, Wang X J, Zhang J, Yang F F, Shi J H, Su L L, Hu D H

Abstract excerpt

Objective: To investigate the effects of hypoxia on the phenotype transformation of human dermal fibroblasts to myofibroblasts and the mechanism. Methods: The third passage of healthy adult human dermal fibroblasts in logarithmic phase were cultured in DMEM medium containing 10% fetal bovine serum for the following five experiments. (1) In experiments 1, 2, and 3, cells were divided into normoxia group and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Collagen Type I
Share to Collagen Type III

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoxia

Share to Myofibroblasts

Share to NF-kappa B

Share to Pyrrolidines

Share to Random Allocation

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 28648041
DOI: 10.3760/cma.j.issn.1009-2587.2017.06.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Effects of hypoxia on the phenotype transformation of human dermal fibroblasts to myofibroblasts and the mechanism].PMID 28648041Read ↗

[Effects of Wnt/beta-catenin signaling on the phenotype change of human dermal fibroblasts and its mechanism].Semantic proximity Read ↗

Hypoxia drives the transition of human dermal fibroblasts to a myofibroblast-like phenotype via the TGF-β1/Smad3 pathway.Semantic proximity Read ↗

[Transforming growth factor-beta1 induced phenotypic differentiation of human lung fibroblasts through mitogen activated protein kinase-dependent pathway].Semantic proximity Read ↗

[The research of fibroblasts from human hypertrophic scar showing a mesenchymal stem cell phenotype and multilineage differentiation potentialities].Semantic proximity Read ↗

[Hypoxia, inflammation and phenotypic plasticity of macrophages: the central role of HIF-1 and NFkappaB].Semantic proximity Read ↗

Effect of Hypoxia on Gene Expression in Cell Populations Involved in Wound HealingSemantic proximity Read ↗

Functional Repercussions of Hypoxia-Inducible Factor-2α in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

[Effects and mechanism of age on the stiffness and the fibrotic phenotype of fibroblasts of human hypertrophic scar].Semantic proximity Read ↗

Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.Semantic proximity Read ↗

[Platelet derived growth factor-BB regulates phenotype transformation of pulmonary artery smooth muscle cells via SIRT3 affecting glycolytic pathway].Semantic proximity Read ↗

[Docosahexaenoic acid inhibits hypoxia-induced pulmonary arterial smooth muscle cells phenotype switching by inhibiting NFATc1 signaling].Semantic proximity Read ↗

[Impact of hyperoxia on the phenotype of pulmonary artery smooth muscle cells].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.