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Article

Genomic variation of human papillomavirus type 16 and risk for high grade cervical intraepithelial neoplasia.

Journal of the National Cancer Institute - 4 Jun 1997

Xi L F, Koutsky L A, Galloway D A, Kuypers J, Hughes J P, Wheeler C M, Holmes K K, Kiviat N B

Abstract excerpt

BACKGROUND: Epidemiologic studies have demonstrated strong and consistent associations between the detection of human papillomavirus (HPV) type 16 DNA and the risk of cervical intraepithelial neoplasia (CIN) and cervical cancer. However, HPV16 is also the most common type of HPV in the normal population, and only a minority of women with HPV16 infection develop cervical cancer. Studies of genomic heterogeneity in...

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PMID: 9182978
DOI: 10.1093/jnci/89.11.796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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