Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of a signature nucleotide sequence of hepatitis C virus for detection of viral RNA in human serum and plasma

1 Nov 1991

Abstract excerpt

The nucleic acid sequence of the putative 5'-untranslated (5PUT) region of hepatitis C virus (HCV), determined for samples obtained from a variety of geographic origins, was found to be over 98% conserved among all isolates. On the basis of this signature sequence for HCV, a viral RNA assay was developed by using cDNA synthesis with reverse transcriptase, followed by polymerase chain reaction (PCR). The new assay...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1663510
DOI: 10.1128/jcm.29.11.2528-2534.1991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of a signature nucleotide sequence of hepatitis C virus for detection of viral RNA in human serum and plasmaPMID 1663510Read ↗

Discovery of the hepatitis C virusSemantic proximity Read ↗

Characterization of the genomic sequence of type V (or 3a) hepatitis C virus isolates and PCR primers for specific detectionSemantic proximity Read ↗

Nucleotide sequence of the genomic RNA of hepatitis C virus isolated from a human carrier: comparison with reported isolates for conserved and divergent regionsSemantic proximity Read ↗

Comparative evaluation of hepatitis C virus RNA quantitation by branched DNA, NASBA, and monitor assays.Semantic proximity Read ↗

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.Semantic proximity Read ↗

Nucleotide sequence of the 5' noncoding region of hepatitis G virus isolated from Japanese patients: comparison with reported isolates.Semantic proximity Read ↗

A second-generation method of genotyping hepatitis C virus by the polymerase chain reaction with sense and antisense primers deduced from the core gene.Semantic proximity Read ↗

Sequence analysis of the 5' noncoding region of hepatitis C virus.Semantic proximity Read ↗

Improved amplification system for detection of hepatitis C virus genome that simultaneously differentiates viral genotypes.Semantic proximity Read ↗

Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay.Semantic proximity Read ↗

Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C.Semantic proximity Read ↗

Detection of hepatitis C virus ribonucleic acid in the serum by amplification with polymerase chain reaction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.