Article
Comparative evaluation of hepatitis C virus RNA quantitation by branched DNA, NASBA, and monitor assays.
Hepatology (Baltimore, Md.) - 1 Feb 1999
Lunel F, Cresta P, Vitour D, Payan C, Dumont B, Frangeul L, Reboul D, Brault C, Piette J C, Huraux J M
Abstract excerpt
Several studies have shown a relationship between pretreatment hepatitis C virus (HCV) viral load and the response to interferon (IFN) therapy, creating a need for quantitative HCV-RNA assays. Here, we compared three commercial methods: nucleic acid sequence-based amplification NASBA (Organon), branched DNA 2.0 (bDNA) (Chiron), and Monitor (Roche), with reverse-transcription polymerase chain reaction (RT-PCR) as...
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