Article
Comparative evaluation of hepatitis C virus RNA quantitation by branched DNA, NASBA, and monitor assays.
Hepatology (Baltimore, Md.) - 1 Feb 1999
Lunel F, Cresta P, Vitour D, Payan C, Dumont B, Frangeul L, Reboul D, Brault C, Piette J C, Huraux J M
Abstract excerpt
Several studies have shown a relationship between pretreatment hepatitis C virus (HCV) viral load and the response to interferon (IFN) therapy, creating a need for quantitative HCV-RNA assays. Here, we compared three commercial methods: nucleic acid sequence-based amplification NASBA (Organon), b...
Topics
- Base Sequence
- DNA
- Gene Amplification
- Genotype
- Hepacivirus
- Hepatitis C
- Hepatitis C Antibodies
- Humans
- Interferons
- Prospective Studies
- RNA, Viral
- Reagent Kits, Diagnostic
- Reproducibility of Results
- Reverse Transcriptase Polymerase Chain Reaction
- Sensitivity and Specificity