Article
Evaluation of cytokine genetic polymorphisms in adult patients with common variable immunodeficiency: A single-center study.
Immunology letters - 1 Aug 2016
Perovic Dijana, Perovic Vladimir, Pravica Vera, Bonaci-Nikolic Branka, Mijanovic Radovan, Bunjevacki Vera
Abstract excerpt
Common variable immunodeficiency (CVID) is a heterogeneous disease characterized by impaired B-cell differentiation and maturation accompanied with the defective antibody production. Several investigators addressed the possibility that disturbed cytokine production of TNF, IL-6, IFN-γ and IL-10,...
Topics
- Adult
- Common Variable Immunodeficiency
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interferon-gamma
- Interleukin-10
- Interleukin-6
- Male
- Polymorphism, Single Nucleotide
- Splenomegaly
- Tumor Necrosis Factor-alpha
