Article
Evaluation of cytokine genetic polymorphisms in adult patients with common variable immunodeficiency: A single-center study.
Immunology letters - 1 Aug 2016
Perovic Dijana, Perovic Vladimir, Pravica Vera, Bonaci-Nikolic Branka, Mijanovic Radovan, Bunjevacki Vera
Abstract excerpt
Common variable immunodeficiency (CVID) is a heterogeneous disease characterized by impaired B-cell differentiation and maturation accompanied with the defective antibody production. Several investigators addressed the possibility that disturbed cytokine production of TNF, IL-6, IFN-γ and IL-10, among a variety of others, may be implicated in CVID. The aim of this study was to test the hypothesis that genetic...
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