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Article

Weak selection and recent mutational changes influence polymorphic synonymous mutations in humans.

Proceedings of the National Academy of Sciences of the United States of America - 2 May 2006

Comeron Josep M

Abstract excerpt

Recent large-scale genomic and evolutionary studies have revealed the small but detectable signature of weak selection on synonymous mutations during mammalian evolution, likely acting at the level of translational efficacy (i.e., translational selection). To investigate whether weak selection, and translational selection in particular, plays any role in shaping the fate of synonymous mutations that are present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16632609
DOI: 10.1073/pnas.0510638103
PMCID: PMC1458998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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