The gene responsible for autoimmune polyglandular syndrome type 1 maps to chromosome 21q22.3 in US patients.

doi:10.1006/jaut.1998.0191

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Article

The gene responsible for autoimmune polyglandular syndrome type 1 maps to chromosome 21q22.3 in US patients.

Journal of autoimmunity - 1 Apr 1998

Chen Q Y, Lan M S, She J X, Maclaren N K

Abstract excerpt

Autoimmune polyglandular syndrome type 1 [APS-1] comprises multiple organ-specific autoimmunities such as acquired hypoparathyroidism and autoimmune Addison's disease, and a predisposition to certain infections such as chronic mucocutaneous candidiasis. An APS-1 candidate gene was assigned to chr...

Topics

Alleles
Arabs
Autoimmune Diseases
Chromosome Mapping
Chromosomes, Human, Pair 21
Endocrine System Diseases
Ethnicity
Europe
Female
Finland
France
Genotype
Haplotypes
Hispanic or Latino
Humans
Lod Score
Male
Microsatellite Repeats

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