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Article

Investigating the genetic determinants of cardiovascular disease using candidate genes and meta-analysis of association studies.

Annals of human genetics - 1 Mar 2006

Casas Juan P, Cooper Jackie, Miller George J, Hingorani Aroon D, Humphries Steve E

Abstract excerpt

Coronary artery disease (CAD) has a polygenic basis, and identification of CAD susceptibility genes has the potential to aid the development of new treatments and enhance prediction of disease risk. Thus far, the strategy has firstly been to choose "candidate" genes coding for important "rate-limiting" proteins in the homeostatic systems involved in maintaining cardiovascular health; secondly to identify common...

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Source

Identifiers

PMID: 16626327
DOI: 10.1111/j.1469-1809.2005.00241.x

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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