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Article

Pharmacogenetic profiling and clinical outcome of patients with advanced gastric cancer treated with palliative chemotherapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Apr 2006

Ruzzo Annamaria, Graziano Francesco, Kawakami Kazuyuki, Watanabe Go, Santini Daniele, Catalano Vincenzo, Bisonni Renato, Canestrari Emanuele, Ficarelli Rita, Menichetti Ettore Tito, Mari Davide, Testa Enrica, Silva Rosarita, Vincenzi Bruno, Giordani Paolo, Cascinu Stefano, Giustini Lucio, Tonini Giuseppe, Magnani Mauro

Abstract excerpt

PURPOSE: To investigate whether polymorphisms with putative influence on fluorouracil/cisplatin activity are associated with clinical outcomes of patients with advanced gastric cancer (AGC). PATIENTS AND METHODS: Peripheral blood samples from 175 prospectively enrolled AGC patients treated with f...

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Identifiers

PMID: 16622263
DOI: 10.1200/JCO.2005.04.8322

Genes

ERCC1
GSTP1
MTHFR
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16622263-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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